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Maintenance IV Fluid Rate (4-2-1 Rule)

Input

Maintenance Fluid Rate

Daily Maintenance Volume

About

The 4-2-1 rule (Holliday-Segar method) is the standard method for calculating maintenance intravenous fluid requirements. It estimates the hourly fluid rate needed to replace normal daily fluid losses from metabolism, respiration, and urinary output. This is the baseline rate; additional fluids may be needed for ongoing losses (e.g., fever, burns, surgical drains).

Formula

First 10 kg of body weight: 4 mL/kg/hr
Next 10 kg (11–20 kg): 2 mL/kg/hr
Each additional kg (>20 kg): 1 mL/kg/hr
Example: 70 kg patient = 40 + 20 + 50 = 110 mL/hr

Interpretation

Weight RangeRateExample
0 – 10 kg4 mL/kg/hr8 kg → 32 mL/hr
11 – 20 kg40 + 2 mL/kg/hr15 kg → 50 mL/hr
> 20 kg60 + 1 mL/kg/hr70 kg → 110 mL/hr

References

  1. Holliday MA, Segar WE. The maintenance need for water in parenteral fluid therapy. Pediatrics. 1957;19(5):823-832.

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Disclaimer

For educational and informational purposes only. Not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional.